Abstract:
Effects of diminazene aceturate and ceftriaxone disodium were evaluated on sperm quality of rams.
Daily intramuscular injections of diminazene (6 mg/kg) or ceftriaxone (28.5 mg/kg) were given to
each of seven Akkaraman rams assigned per drug for two days. Semen samples were collected
from the rams at post-treatment 1, 4, 24, 48, 72, 144, 288 and 336 h and examined for sperm
characteristics and hyaluronidase activity. Results showed that use of ceftriaxone and diminazene
caused significant (P < 0:01) decreases in sperm concentration, volume and motility compared to
control group within 288 h post-treatment. In addition, hyaluronidase activity increased significantly
(P < 0:01) in semen of rams treated with ceftriaxone while remained unchanged in those received
diminazene. In conclusion, diminazene aceturate and ceftriaxone disodium did not have any
deleterious effect on hyaluronidase enzyme. However, both drugs caused impairment of sperm in
rams during the 288 h.
