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Effects of levamisole on hyaluronidase activity and sperm characteristics in rams


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dc.contributor.author Bozkurt, T
dc.contributor.author Tanyıldızı, S
dc.contributor.author Türk, G
dc.date.accessioned 2015-06-12T12:34:00Z
dc.date.available 2015-06-12T12:34:00Z
dc.date.issued 2004
dc.identifier.citation Bozkurt, T., Tanyıldızı, S. ve Türk, G. (2004). Effects of levamisole on hyaluronidase activity and sperm characteristics in rams. Theriogenology, 62(1-2), 323-329. tr_TR
dc.identifier.uri http://hdl.handle.net/11508/8019
dc.description.abstract The aim of this study was to determine the effects of levamisole on sperm characteristics and hyaluronidase activity of blood serum and semen. For this purpose, 12 Akkaraman rams (2–3 years old) were used. Levamisole hydrochloride was administered orally at a dose of 7.5 mg/kg body weights once daily for 2 days. Serum and semen samples were collected from the rams at posttreatment 1, 2, 4, 24, 48, 72, 96, 120, 144, 216, 288 and 384 h and examined for sperm characteristics and hyaluronidase activity. The results showed that the use of levamisole caused significant (P < 0:01) increase in serum hyaluronidase activity at all times except the 72 h, and in semen hyaluronidase activity at 1, 2, 4, 24, 72, 96 and 120 h compared to the control group. In addition, the levamisole caused significant (P < 0:05) decreases in semen volume, sperm motility, concentration and total sperm number at all times. There was no correlation between semen hyaluronidase activity and the sperm characteristics. In conclusion, levamisole did not have any deleterious effect on hyaluronidase enzyme. However, the use of this drug in rams during the breeding season is harmful due to the decrease of sperm characteristics. tr_TR
dc.language.iso İngilizce tr_TR
dc.subject Fırat Üniversitesi Kütüphanesi::TIP BİLİMLERİ tr_TR
dc.subject.ddc levamisole, sperm, ram tr_TR
dc.title Effects of levamisole on hyaluronidase activity and sperm characteristics in rams tr_TR
dc.type Makale - Bilimsel Dergi Makalesi - Çok Yazarlı tr_TR
dc.contributor.YOKID TR146975 tr_TR
dc.contributor.YOKID TR4550 tr_TR
dc.contributor.YOKID TR56229 tr_TR
dc.relation.journal Theriogenology tr_TR
dc.identifier.volume 62 tr_TR
dc.identifier.issue 1-2 tr_TR
dc.identifier.pages 323;329
dc.published.type Uluslararası tr_TR


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University of Fırat
23119
Elazığ-Merkez
TURKEY